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   1992| April-June  | Volume 10 | Issue 2  
    Online since November 3, 2009

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Natural History Of Phyllanthus Amarus In The Treatment Of Hepatitis B
S.P Thyagarajan, S Jayaram
April-June 1992, 10(2):64-80
Full text not available  [PDF]
  567 922 -
Antibiotic Susceptibility Pattern Of Bacteria Isolated From Urinary Tract Infection With Special Reference To Norfloxacin
Rashmi Kandhari, Bibhabati Mishra, Anandita Mandal
April-June 1992, 10(2):91-93
Norfloxacin, a quinolone derivative inhibits most of the gram positive and gram negative bacteria responsible for U. T. I. 715 fresh urinary isolates of Escherichia coli (244) Klebsiella sp. (196) Pseudomonas aeruginosa (85) Proteus sp. (53), Acinetobacter sp. (3). Staphylococcus aureus (110) Staphylococcus epidermidis (9) and Streptococcus faecalis (15) were tested sensitivity to Norfloxacin and other commonly used antibiotics by disc agar diffusion. Escherichia coli, Klebsiella sp. And Pseudomonas aeruginosa were more sensitive to Norfloxacin, 82%, 78% and 79% respectively, as compared to other drugs. MIC 90 of 20 strains each of Escherichia coli., Klebsiella sp. And Pseudomonas aeruginosa were calculated by agar dilution method for Norfloxacin. Average MIC 90 for Escherichia coli. Was 0.5 mg/1, for Klebsiella sp. 2 mg/1 and for Pseudomonas aeruginosa 2 mg/1.
[ABSTRACT]   Full text not available  [PDF]
  770 226 -
Prevalence Of Mycoplasma In Female Genital Tract Infections
Neeru Singla, Shashi Kanta, Prem Singla
April-June 1992, 10(2):122-125
Seventy-five female patients with genital tract infections and twenty-five healthy females, who served as control, were investigated for the association of Mycoplasma. Twenty-four (32%) of the study group were positive for Mycoplasma species. M. Hominis was present in 7(9.3%) Ureaplasma urealyticum in 4(6.3%); mixed Mycoplasma spp. In 2(2.6%); Mycoplasma with N. gonorrhoeae-1 (1.3%); U. urealyticum with C. albicans-8 (10.6%) and un typed Mycoplasma in 2(2.6%). While in control group, 2 cases (8%) of Urea plasma urealyticum and 1 (4%) of Mycoplasma hominis was present. This difference of isolation of Mycoplasma in study and control group was statistically significant (P<0.001).
[ABSTRACT]   Full text not available  [PDF]
  828 74 -
Significance Of IgG Antibody Of Mycobacterium Tuberculosis Antigen 5 In Cerebrospinal Fluid Of Patients With Chronic Meningitis
A Mathai, V.V Radhakrishnan, Molly Thomas, Shobha Sehgal
April-June 1992, 10(2):94-100
In a prospective study, an enzyme - linked immunosorbent assay (ELISA), for the detection of lgG antibody of Mycobacterium tuberculosis antigen 5 was used on cerebrospinal fluid (CSF) specimens from fifty patients with a clinical diagnosis of chronic meningitis. CSF from ten culture proven patients with tuberculous meningitis (TBM) and CSFs from fifty patients with non-tuberculous neurological diseases were selected as positive and negative controls. IgG antibody to antigen5 was demonstrated in significant titers (80-640) in CSFs of positive controls. In the negative controls, ELISA gave of negative result at 1 in 80. In nine out of fifty patients with chronic meningitis, the ELISA gave positive results and the antibody titers in CSFs in these nine patients ranged between 80-640. Anti-tuberculosis chemotherapy was instituted in these nine patients for four weeks during their hospital stay. At the time of follow-up, six out of nine patients showed improvement in their clinical status. The remaining three patients expired during the hospital stay and the diagnosis of TBM was confirmed at autopsy. The result of this study emphasizes the potential application of ELISA either to establish a tuberculous a etiology of its exclusion in patients with chronic meningitis.
[ABSTRACT]   Full text not available  [PDF]
  681 44 -
Characterization Of R Plasmids In Salmonella Senftenberg Isolated During An Outbreak In Pediatric Ward
Mohd.Najeeb Siddiqui, Ashok Rattan, S.M Hadi, M.A.M Faridi, M.A Malik, Abida Malik
April-June 1992, 10(2):114-117
Eighteen strains of Salmonella senftenberg, an uncommon serotype, were isolated from the stools of children attending the pediatrics clinics of JN Medical College Hospitals, AMU, Aligarh between January and May. All strains were multiple drug resistance. The commonest pattern was ACSTK (56.6%) followed by ACKT (22.3%). The MIC 90 against Ampicillin and chloramphenicol of these isolates was more than 500 ug/ml. The resistance could be cured following UV light or Acridine Orange treatment in some of these strains. The R plesmids did not have the property of auto-transfer when incubated with E. coli K 12, but could be mobilized by X factor with a mean frequency of 0.84 X 10-5, only ACKT could be transferred en bloc. Plasmid DNA was isolated from all the eighteen strains. All isolates had only one plasmid, which was determined to have a molecular weight of 48 kb.
[ABSTRACT]   Full text not available  [PDF]
  633 39 -
Control Of Rheumatic Fever And Rheumatic Heart Disease In Children Through Primary Health Centres & School Health Surveys
R Gupta, K Prakash, A.K Kapoor
April-June 1992, 10(2):81-84
We carried out the control programme of rheumatic fever and rheumatic heart disease (RF/RHD) during May’90 May’91 in villages of Delhi, utilizing the existing health services of Primary health centers and school health services. 749 children studying in schools aged 5-15 years were examined clinically and investigated for evidence of group A streptococcal (GAS) pharyngitis. We observed that although all these children were a symptomatic, 103 were positive for group A streptococci. Out of these 103 children, blood samples of 53 children were screened for anti-streptolysin O and antideoxyribonuclease B titer; 54.7% showed significant titers indicating sub clinical GAS infection. All these children were given primary prophylaxis. Total of 5238 children in the age group of 5-15 years attending primary health centers out patient department were screened for evidence of RHD; of which 3 were established cases of RHD and 41 suspected cases were referred to cardiologist for confirmation. After confirmation of diagnosis all these cases were registered and were put on secondary prophylaxis. This is evident from our study that RF/RHD control programme is essential and can be carried out through primary health centers and school health scheme.
[ABSTRACT]   Full text not available  [PDF]
  575 69 -
Transfer Of Infectious Drug Resistance - An In Vivo Study
Mamatha Shetty, K.L Bairy, P.G Shivananda
April-June 1992, 10(2):85-90
In the present study, the in vivo transfer of drug resistance from resistant donor Escherichia coil strains to E, coli K12 and Salmonella typhimurium recipients in the gut of suckling rat is being reported. The frequency of transfer from E. coli to S. typhimurium 209 was found to be greater in comparison to recipient E. coli K12. Among the animal models used, transferable drug resistance took place at a higher rate in the suckling rat when compared to other animals like adult rabbit, suckling rabbit, adult mice etc. Single drug transfer was found to occur more often (20%) compared to double drug transfer in S. typhimurium (4.4%). The overall incidence of antibiotic resistance transfer by E. coli donors to both recipients was fairly high.
[ABSTRACT]   Full text not available  [PDF]
  596 41 -
An Epidemic Of Cholera In Himachal Pradesh
Asha Goyal, Vijay Sharma, Tej Singh Thakur
April-June 1992, 10(2):118-121
Himachal Pradesh was free from cholera till July, 1998 when 4 cases of cholera were reported from I.G. Medical College, Shimla. In the year 1991 a total of 5,709 cases of cholera and 119 deaths occurred in the state during the period June to September, giving an overall case fatality rate of 2.08 per cent. Of the 83 rectal swabs, Vibro cholera EITor, phage Type T2 (two) was isolated from 36. All the strains were sensitive to all antibiotics tested. This is the first report of cholera epidemic from the state.
[ABSTRACT]   Full text not available  [PDF]
  582 53 -
R-Factor Mediated Multiple Drug Resistance In S.Typhi Strains Isolated For Seven Years
Vinod Kaul
April-June 1992, 10(2):107-113
Two hundred and two strains of Salmonella typhi isolated from pediatric patients, during the years 1982 to 88, were studied for drug resistance and transferable R-plasmids. Of these, 185 (91.5 per cent) were drug resistant, 31 (16.7 per cent) were multiple drug resistant and 23 (12.4 per cent) were resistant to chloramphenicol. The minimal inhibitory concentration for chloramphenicol ranged between 64 to 256 mcg/ml. The isolation of multiple drug resistant strains increased significantly from years 1982 to ’88, Ampicillin and tetracycline resistant strains increased two fold, whereas, chloramphenicol and co-trimoxazole resistant strains increased to 4.94 and 3.83 fold respectively. The most common resistance pattern among multiple drug resistant strains was ampicillin, tetracycline, sulfamethoxazole plasmids were more prevalent in multi drug resistant strains. Furthermore, transferability of R-plasmids from multi drug resistant intestinal Escherichia coli to sensitive S. typhi was also observed. The frequency of transfer was low with S. typhi (between 1 X 10 6 to 5.6 X 10-7) as compared to E. coli (1.1 to 10-2 to 3.6 X 10-3).
[ABSTRACT]   Full text not available  [PDF]
  545 36 -
Isolation Of Live Adult Filarial Worm From The Spermatic Cord In A Patient With Inguinal Hernia - A Case Report
Subramania N Sivam, V.H Balasangameswar, R Sambasiva Rao, A Kakar, N Ananthakrishnan
April-June 1992, 10(2):139-140
Finding the adult filarial worm in histopathological sections of lymph nodes and other tissues is not very uncommon in an area endemic for lymphatic filariasis. However, the isolation of a live worm is very unusual and is hitherto not reported. There have been few case reports of isolation of adult Loa loa worm from the eye1.
[ABSTRACT]   Full text not available  [PDF]
  522 42 -
Experimental Induction Of Cervical Carcinoma By Herpes Simplex Virus Type-2 In Rabbits : Gynaecological, Cytopathological And Immunological Evaluations.
M Elanchezhiyan, K Udayasankar, P Rajendran, S Subramanian, S.P Thyagarajan
April-June 1992, 10(2):126-132
Evaluation of rabbits as experimental animal model for Herpes simplex virus type-2 (HSV-2) (HV-219 Strain) induced cervical carcinoma resulted in the development of a neoplastic condition in the form of leukoplakic patches only. On Papanicolaou’s staining, these areas revealed intra-nuclear vacuolization. The production of leukoplakic changes correlated with increase in the antibody level against HSV-2.
[ABSTRACT]   Full text not available  [PDF]
  487 39 -
Burcellosis In Alappuzha - Report Of 2 Cases
Sumangala M Bal
April-June 1992, 10(2):133-134
Two cases of brucellosis from Kerala are reported. Both the cases gave the history of contact with sheep before the development of the disease. Brucella melitensis biotype I was isolated in the first case. It is the first report of isolation of B. Melitensis in Kerala.
[ABSTRACT]   Full text not available  [PDF]
  474 47 -
Generalized Rhinosporidiosis : A Case Report
J Mahanta, N.C Deka, T.K Das
April-June 1992, 10(2):135-138
A case of generalized rhinosporidiosis is reported. Patient reported with swelling over eyelid, face, chest wall and thigh. Excision biopsies from multiple sites showed sporangium of different sizes and trophocytes at different stages of development. Diagnosis of generalized rhinosporidiosis was made.
[ABSTRACT]   Full text not available  [PDF]
  468 46 -
Failure To Isolate Verotoxin Producing Escherichia Coli From Patients Of Haemolytic Uremic Syndrome
K Kishore, A Rattan, A Bagga, N Manjunath, R.N Srivastava
April-June 1992, 10(2):101-106
Haemolytic Uremic syndrome which is characterized by the triad of acute renal failure, thrombocytopenia and haemolytic anemia following a diarrhoeal episode has been reported from all parts of India. We investigated 28 HUS patients and 25 healthy age and sex matched controls in order to determine whether verocytotoxin producing Escherichia coli infection precipitated the syndrome in India. We were unable to isolate any verocytotoxin producing E. coli from our patients or controls. The possible reason could be the delay between the start of symptoms and sample collection, by which time the BTEC bacteria as well as Verotoxin would have been cleared. Serology for detection of anti lip polysaccharide antibodies may be of use in these cases.
[ABSTRACT]   Full text not available  [PDF]
  459 39 -
Advances In Laboratory Diagnosis Of Amoebiasis
R.C Mahajan, R Sehgal
April-June 1992, 10(2):62-63
Full text not available  [PDF]
  263 63 -

2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

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