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Year : 2020  |  Volume : 38  |  Issue : 3  |  Page : 351--356

Epidemiological pattern of Malassezia, its phenotypic identification and antifungal susceptibility profile to azoles by broth microdilution method

Packia Nancy Romald1, Anupma Jyoti Kindo1, V Mahalakshmi2, U Umadevi3 
1 Department of Microbiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India
2 Department of Dermatology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India
3 Department of Microbiology, Madras Medical College, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Anupma Jyoti Kindo
Department of Microbiology, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai – 116, Tamil Nadu
India

Background: Malassezia though known for its cutaneous infections can potentially cause invasion. The skin infections caused by Malassezia have poor patient compliance due to its chronicity and recurrent nature of the disease. There is also a lack of standardised antifungal susceptibility profile for Malassezia due to its complex growth requirement. Objective: This study was performed to understand the epidemiological pattern of disease and to study the antifungal susceptibility testing (AFST) profile so as to choose the appropriate drug/drugs to treat the infections caused by Malassezia. Materials and Methods: Samples were collected and processed, species were identified by conventional method and AFST was done by broth microdilution method. Results: The epidemiological pattern showed adolescent females commonly affected in torso. The most common lesion was pityriasis versicolor. The systemic antifungal of choice was itraconazole with the lowest minimum inhibitory concentration (MIC) of 0.125–1 μg/ml. The best topical drug with the lowest MIC value was clotrimazole 0.03–0.5 μg/ml. Conclusion: AFST is important as it will help the dermatologist to choose the appropriate antifungal agents for the patient and thereby reduce the chronicity of the disease with good patient compliance

How to cite this article:
Romald PN, Kindo AJ, Mahalakshmi V, Umadevi U. Epidemiological pattern of Malassezia, its phenotypic identification and antifungal susceptibility profile to azoles by broth microdilution method.Indian J Med Microbiol 2020;38:351-356

How to cite this URL:
Romald PN, Kindo AJ, Mahalakshmi V, Umadevi U. Epidemiological pattern of Malassezia, its phenotypic identification and antifungal susceptibility profile to azoles by broth microdilution method. Indian J Med Microbiol [serial online] 2020 [cited 2021 Mar 2 ];38:351-356
Available from: https://www.ijmm.org/article.asp?issn=0255-0857;year=2020;volume=38;issue=3;spage=351;epage=356;aulast=Romald;type=0