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Year : 2016  |  Volume : 34  |  Issue : 3  |  Page : 275--285

The changing face of community-acquired methicillin-resistant Staphylococcus aureus

P Kale, B Dhawan 
 Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
B Dhawan
Department of Microbiology, All India Institute of Medical Sciences, New Delhi
India

Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of infection, both in hospitalised patients with significant healthcare exposure and in patients without healthcare risk factors. Community-acquired methicillin-resistant S. aureus (CA-MRSA) are known for their rapid community transmission and propensity to cause aggressive skin and soft tissue infections and community-acquired pneumonia. The distinction between the healthcare-associated (HA)-MRSA and CA-MRSA is gradually fading owing to the acquisition of multiple virulence factors and genetic elements. The movement of CA-MRSA strains into the nosocomial setting limits the utility of using clinical risk factors alone to designate community or HA status. Identification of unique genetic characteristics and genotyping are valuable tools for MRSA epidemiological studies. Although the optimum pharmacotherapy for CA-MRSA infections has not been determined, many CA-MRSA strains remain broadly susceptible to several non-β-lactam antibacterial agents. This review aimed at illuminating the characteristic features of CA-MRSA, virulence factors, changing clinical settings and molecular epidemiology, insurgence into the hospital settings and therapy with drug resistance.

How to cite this article:
Kale P, Dhawan B. The changing face of community-acquired methicillin-resistant Staphylococcus aureus.Indian J Med Microbiol 2016;34:275-285

How to cite this URL:
Kale P, Dhawan B. The changing face of community-acquired methicillin-resistant Staphylococcus aureus. Indian J Med Microbiol [serial online] 2016 [cited 2021 Mar 3 ];34:275-285
Available from: https://www.ijmm.org/article.asp?issn=0255-0857;year=2016;volume=34;issue=3;spage=275;epage=285;aulast=Kale;type=0