Indian Journal of Medical Microbiology Home 

REVIEW ARTICLE
[View FULLTEXT] [Download PDF]
Year : 2007  |  Volume : 25  |  Issue : 2  |  Page : 93--102

Edible vaccines: Current status and future

P Lal1, VG Ramachandran1, R Goyal1, R Sharma2 
1 Departments of Microbiology, University College of Medical Sciences, Guru Teg Bahadur Hospital, New Delhi - 110 095, India
2 Departments of Pediatrics, University College of Medical Sciences, Guru Teg Bahadur Hospital, New Delhi - 110 095, India

Correspondence Address:
R Goyal
Departments of Microbiology, University College of Medical Sciences, Guru Teg Bahadur Hospital, New Delhi - 110 095
India

Edible vaccines hold great promise as a cost-effective, easy-to-administer, easy-to-store, fail-safe and socioculturally readily acceptable vaccine delivery system, especially for the poor developing countries. It involves introduction of selected desired genes into plants and then inducing these altered plants to manufacture the encoded proteins. Introduced as a concept about a decade ago, it has become a reality today. A variety of delivery systems have been developed. Initially thought to be useful only for preventing infectious diseases, it has also found application in prevention of autoimmune diseases, birth control, cancer therapy, etc. Edible vaccines are currently being developed for a number of human and animal diseases. There is growing acceptance of transgenic crops in both industrial and developing countries. Resistance to genetically modified foods may affect the future of edible vaccines. They have passed the major hurdles in the path of an emerging vaccine technology. Various technical obstacles, regulatory and non-scientific challenges, though all seem surmountable, need to be overcome. This review attempts to discuss the current status and future of this new preventive modality.

How to cite this article:
Lal P, Ramachandran V G, Goyal R, Sharma R. Edible vaccines: Current status and future.Indian J Med Microbiol 2007;25:93-102

How to cite this URL:
Lal P, Ramachandran V G, Goyal R, Sharma R. Edible vaccines: Current status and future. Indian J Med Microbiol [serial online] 2007 [cited 2020 Nov 25 ];25:93-102
Available from: https://www.ijmm.org/article.asp?issn=0255-0857;year=2007;volume=25;issue=2;spage=93;epage=102;aulast=Lal;type=0