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Year : 2007  |  Volume : 25  |  Issue : 2  |  Page : 146--149

Prevalence of central nervous system cryptococcosis in human immunodeficiency virus reactive hospitalized patients

V Lakshmi, T Sudha, VD Teja, P Umabala 
 Department of Microbiology, Nizam's Institute of Medical Sciences, Hyderabad - 500 082, India

Correspondence Address:
V Lakshmi
Department of Microbiology, Nizam«SQ»s Institute of Medical Sciences, Hyderabad - 500 082
India

Central nervous system cryptococcosis is an important cause of mortality among human immunodeficiency virus (HIV) reactive patients. A retrospective study was conducted on a total of 1,863 HIV reactive hospitalized patients suspected of cryptococcal meningitis. Three hundred and fifty-nine cerebrospinal fluid specimens of these cases were screened for various cryptococcal investigations. Thirty-nine out of 359 (10.86%) showed a definite diagnosis of cryptococcosis with a mortality rate of 25.64%. Prevalence of cryptococcal meningitis in the total HIV reactive cohort was 2.09%. Concurrent cryptococcal meningitis and tuberculosis was seen in 33.3% cases. A high index of clinical suspicion and routine mycological surveillance is required to help an early diagnosis and appropriate therapy, as majority of patients respond well to therapy if treated early.

How to cite this article:
Lakshmi V, Sudha T, Teja V D, Umabala P. Prevalence of central nervous system cryptococcosis in human immunodeficiency virus reactive hospitalized patients.Indian J Med Microbiol 2007;25:146-149

How to cite this URL:
Lakshmi V, Sudha T, Teja V D, Umabala P. Prevalence of central nervous system cryptococcosis in human immunodeficiency virus reactive hospitalized patients. Indian J Med Microbiol [serial online] 2007 [cited 2020 Oct 31 ];25:146-149
Available from: https://www.ijmm.org/article.asp?issn=0255-0857;year=2007;volume=25;issue=2;spage=146;epage=149;aulast=Lakshmi;type=0