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Year : 2007  |  Volume : 25  |  Issue : 1  |  Page : 24--27

Serological evaluation of leptospirosis in Hyderabad, Andhra Pradesh: A retrospective hospital-based study

S Velineni1, S Asuthkar1, P Umabala2, V Lakshmi2, M Sritharan1 
1 Department of Animal Sciences, School of Life Sciences, University of Hyderabad, Hyderabad - 500 046, India
2 Department of Microbiology, Nizam's Institute of Medical Sciences, Hyderabad - 500 082, Andhra Pradesh, India

Correspondence Address:
M Sritharan
Department of Animal Sciences, School of Life Sciences, University of Hyderabad, Hyderabad - 500 046
India

Purpose : Leptospirosis is a zoonotic disease with humans getting the infection either from rodent hosts or from domestic animals. Urine contaminated environment is the common source of infection. This is an under-reported disease in Andhra Pradesh. We report a retrospective hospital-based study on 55 patients with suspected leptospirosis. Methods : A total of 55 serum samples were collected from patients with suspected leptospirosis and subjected to serological testing by LeptoTek Dri-dot, microscopic agglutination test (MAT) and IgM enzyme-linked immunosorbent assay (ELISA). Identification of the predominant infecting serotype was done using a panel of 12 serovars. Results: MAT analysis of all the 55 samples identified all cases to be positive. The predominant serogroup was Icterohaemorrhagiae (68%) followed by Australis (22%), Autumnalis (8%) and Javanica (2%). LeptoTek Dri-dot showed a sensitivity of 96% as compared to MAT. IgM ELISA done on 32 samples showed a sensitivity of 86.7% compared to MAT. Conclusions : MAT helped to identify Icterohemorrhagiae as the predominant serovar in this study. Despite the small number of samples analyzed, the data obtained establishes a need for a prospective study in this region.

How to cite this article:
Velineni S, Asuthkar S, Umabala P, Lakshmi V, Sritharan M. Serological evaluation of leptospirosis in Hyderabad, Andhra Pradesh: A retrospective hospital-based study.Indian J Med Microbiol 2007;25:24-27

How to cite this URL:
Velineni S, Asuthkar S, Umabala P, Lakshmi V, Sritharan M. Serological evaluation of leptospirosis in Hyderabad, Andhra Pradesh: A retrospective hospital-based study. Indian J Med Microbiol [serial online] 2007 [cited 2020 Dec 3 ];25:24-27
Available from: https://www.ijmm.org/article.asp?issn=0255-0857;year=2007;volume=25;issue=1;spage=24;epage=27;aulast=Velineni;type=0