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Year : 2004  |  Volume : 22  |  Issue : 1  |  Page : 66-

Seroprevalence of HIV in a hospital based population and blood bank donors in South India

MU Rasheed, K Hemalatharao 
 Microbiology Department, Medwin Hospitals, Nampally, Hyderabad - 500 001, India

Correspondence Address:
K Hemalatharao
Microbiology Department, Medwin Hospitals, Nampally, Hyderabad - 500 001
India

How to cite this article:
Rasheed M U, Hemalatharao K. Seroprevalence of HIV in a hospital based population and blood bank donors in South India.Indian J Med Microbiol 2004;22:66-66

How to cite this URL:
Rasheed M U, Hemalatharao K. Seroprevalence of HIV in a hospital based population and blood bank donors in South India. Indian J Med Microbiol [serial online] 2004 [cited 2020 Nov 25 ];22:66-66
Available from: https://www.ijmm.org/text.asp?2004/22/1/66/8068

Full Text

Dear Editor,

AIDS is now recognized as a burning health problem worldwide. Andhra Pradesh is the only state in India where more than 2% of all adults are estimated to be infected, which accounts for nearly 400,000 persons.[1] The purpose of this study was to estimate the seroprevalence of HIV in a hospital based population and blood bank donors, and to diagnose opportunistic infections in HIV positive patients. A total number of 5855 serum samples collected from out patient department, in-patients and blood bank donors were processed by ELISA and HIV TRI-DOT rapid method. Sixty reactive samples were confirmed by Western blot method. Different samples of 41 AIDS patients (sputum, urine, blood, throat swab, Foley's catheter tip, tracheal aspiration, pus, pleural fluid, stool and FNAC lymph node) were studied by standard microbiological techniques to determine opportunistic infections.

The seroprevalence rates among males and females from general population were 4.3% and 2%, and from blood bank donors were 0.14% and 0%. In general population, there was a significant difference between the seroprevalence of males (76.56%) and females (23.5%). The highest seroprevalence was found to be among males (8.5%) and females (5.2%) of the age group 21-30 years. In this study, two male children and one female child in the age group between 0-10 were also found reactive. All three were of four years of age. By Western blot, 2 out of 60 cases were HIV-I indeterminate, 2 were HIV-II, 5 were mixed (HIV-I and II), and 43 were HIV-I seropositive.

Results of direct microscopy of clinical samples revealed, gram negative bacilli in 10/26 (38.4%), capsulated gram positive diplococci in 1/26 (3.84%), Candida in 5/12 (41.6%), acid fast bacilli in 3/30 (10%), Cryptococcus neoformans in 1/11 (9.1%) and Cryptosporidium in 1 patient. In culture, Escherichia spp. were predominant, [E.coli-3 (6.25%), E.vulneris-2 (4.16%)], followed by Klebsiella aerogenes, K.ozaenae, Kluvyera acorbata, Pseudomonas fluorescence, P.putida, Streptococcus vestibularis, 1 each (2.08%) in number. Candida in 7 (14.6%), patients was the only fungal isolate.

About 80% of the HIV reactive cases occurs in sexually active and economically productive (15 to 44 years) age group predominantly in men.[2],[3] Various types of infections seen in HIV patients included bacterial, fungal and parasitic infections. Our findings are similar to those reported earlier.[2],[3]

References

1Propoor infotech Centre Trust, AP sitting on AIDS time bomb: state panel (Propoor web site) November 23, 2002. Available at www.propoor.org/news/xar1123.asp. Accessed March 5, 2003.
2AIDS in India. Last updated February 2, 2003. Available at www.avert.org/aidsindia.html. Accessed March 26, 2003.
3Current status of HIV/AIDS epidemic in India: 2002, National AIDS Control Organisation, Ministry of Health & Family Welfare, Government of India, New Delhi.