Indian Journal of Medical Microbiology Home 

Year : 1988  |  Volume : 6  |  Issue : 4  |  Page : 337--341

Antifungal Susceptibility Testing In Otomycoses

C Rodrigues1, V. C Ohri2, D Raghunath3 

Correspondence Address:
C Rodrigues

Fungal aetiology was proved in 50 out of 63 clinically suspected cases of otomycosis. Fungi isolated were aspergillus niger (39), Aspergillus fumigatus (6), Penicillum spp (4) and Candida albicans (1). Antifungal susceptibility testing was performed by agar dilution method against amphotericin B. nystatin, clotrimazole, miconazole and 5-fluorocytosine (5 FC). The commonest isolate, Aspergillus niger was most susceptible to clotrimazole (mean MIC 2.7 mg/1) and in decreasing order to amphotericin B (3.16 mg/1), miconazole (3.66 mg/1), nystatin (4.2 mg/1) and FC (range of MIC 12.5 to > 50 mg/1). Clotrimazole showed satisfactory MIC values for other fungi as well. Mean MIC values against Aspergillus fumigatus were clotrimazole 2.21 mg/1, miconazole and nystatin 3.64 mg/1, amphotericin B, 3.90 mg/1, 5 Fc 12.5 - > 50 mg/1. mean MIC values against penicillium were clotrimazole 2.15 mg/1, miconazole 2.54 mg/1, 5 FC 3.51 mg/1, nystatin 3.90 mg/1, amphotericin B 4.69 mg/1. The methodology of antibiotic susceptibility testing of mycelial fungi is illustrated.

How to cite this article:
Rodrigues C, Ohri V, Raghunath D. Antifungal Susceptibility Testing In Otomycoses.Indian J Med Microbiol 1988;6:337-341

How to cite this URL:
Rodrigues C, Ohri V, Raghunath D. Antifungal Susceptibility Testing In Otomycoses. Indian J Med Microbiol [serial online] 1988 [cited 2020 Nov 23 ];6:337-341
Available from:;year=1988;volume=6;issue=4;spage=337;epage=341;aulast=Rodrigues;type=0