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Year : 2020  |  Volume : 38  |  Issue : 3  |  Page : 485-488

Adrenal histoplasmosis in immunocompetent individuals a case series from the North-Western part of India, Rajasthan province: An emerging endemic focus

1 Department of Endocrinology, SMS Medical College, Jaipur, Rajasthan, India
2 Department of Medicine, SP Medical College, Bikaner, Rajasthan, India
3 Department of Endocrinology, BLDE Medical College, Vijayapur, Karnataka, India
4 Department of Pathology, SMS Medical College, Jaipur, Rajasthan, India

Correspondence Address:
Dr. Balram Sharma
N-17, Navya Path, Gandhi Nagar, Jaipur - 302 015, Rajasthan
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijmm.IJMM_20_280

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Histoplasmosis is a fungal infection caused by Histoplasma capsulatum and very few cases reported from North-West India. Adrenal histoplasmosis is an even more uncommon mycotic disease. We describe five immunocompetent men with adrenal histoplasmosis presenting with constitutional symptoms. Four patients had bilateral adrenal involvement, whereas one had unilateral adrenal mass. Three patients had adrenal insufficiency at presentation and the other two developed adrenal insufficiencies during follow-up. All the patients received amphotericin B and itraconazole treatment which led to symptomatic improvement but adrenal insufficiency persisted in all patients at the end of the follow-up.


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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

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