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Year : 2015  |  Volume : 33  |  Issue : 4  |  Page : 599-600

Unusual fungal sepsis of Alternaria alternata in acute lymphoblastic leukaemia in an adult patient

1 Department of Laboratory Medicine, Max Super Speciality Hospital, Patparganj, New Delhi, India
2 Institute of Laboratory Sciences, Max Super Speciality Hospital, Saket, New Delhi, India

Correspondence Address:
S Jain
Department of Laboratory Medicine, Max Super Speciality Hospital, Patparganj, New Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0255-0857.167324

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We report a case of unusual fungal sepsis of Alternaria alternata in a patient of acute lymphoblastic leukaemia in 62-year-old male who presented with complaints of 'off and on' fever with decreased oral intake. On evaluation, haemogram showed low platelet count and 68% blast cells in peripheral blood. On flow cytometry of peripheral blood, the gated blasts (approximately 55%) highly express CD45, CD10, CD19, CD22 and condition was diagnosed as acute lymphoblastic leukaemia. He was started on standard induction treatment along with supportive therapies. During the course of treatment, two sets of paired blood cultures were sent 48 h apart. All of blood cultures were done on Bac-T alert 3D system. All of them yielded fungus. The fungus was then grown on Sabouraud's Dextrose agar media. It was identified as A. alternata. The patient condition worsened and later had cardiac arrest in ICU and could not be revived.


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2004 - Indian Journal of Medical Microbiology
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