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Year : 2009  |  Volume : 27  |  Issue : 1  |  Page : 48-50

High prevalence of Hepatitis A virus antibody among Bangladeshi children and young adults warrants pre-immunization screening of antibody in HAV vaccination strategy

Department of Virology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahabag, Dhaka, Bangladesh

Correspondence Address:
S U Munshi
Department of Virology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahabag, Dhaka
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Source of Support: None, Conflict of Interest: None

PMID: 19172060

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Serum samples from 465 subjects aged between 1 and 25 years were tested for antibody against hepatitis A virus (HAV) [anti-HAV IgG and IgM] to determine the seroprevalence of HAV antibody and do a cost-benefit analysis for decision making about vaccination against HAV among the general population of Bangladesh. A high prevalence of anti-HAV (74.8%) was observed in the study population; the whole study population was found positive for anti-HAV by the age of 25 years. On performing the cost-benefit analysis, it was found that the cost for vaccination with screening for anti-HAV was almost three times cheaper than vaccination without screening. Thus, in the present socioeconomic condition of Bangladesh, a policy based on screening for HAV antibody before vaccination is recommended.


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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04