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Year : 2004  |  Volume : 22  |  Issue : 3  |  Page : 172-174

Extended spectrum -lactamases in urinary isolates of escherichia coli and klebsiella pneumoniae - Prevalence and susceptibility pattern in a tertiary care hospital

Department of Microbiology, PSG Institute of Medical Sciences and Research, Coimbatore - 641 004, Tamil Nadu, India

Correspondence Address:
S Babypadmini
Department of Microbiology, PSG Institute of Medical Sciences and Research, Coimbatore - 641 004, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

PMID: 17642726

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A total of 411 urinary isolates (353 Escherichia coli and 58 Klebsiella pneumoniae) were studied for extended spectrum -lactamase (ESBL) production by double disk approximation test and NCCLS confirmatory test. ESBL production was found to be 41% in E.coli and 40% in K.pneumoniae. Fourteen percent and 12% of ESBL producers showed false susceptibility to ceftazidime and cefotaxime in routine susceptibility testing. The susceptibility of ESBL producers to imipenem, nitrofurantoin and amikacin was found to be 100%, 89% and 86% respectively. A high degree of associated resistance to gentamicin, co-trimoxazole and quinolones was found in ESBL producers. Majority of ESBL producers was detected among patients admitted in medical ICU and surgery ward.


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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04