| BRIEF COMMUNICATION |
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| Year : 2003 | Volume
: 21
| Issue : 3 | Page : 196-198 |
Emergence of low level vancomycin resistance in MRSA
S Assadullah, DK Kakru, MA Thoker, FA Bhat, N Hussain, A Shah
Department of Clinical Microbiology, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir - 190 011, India
Correspondence Address:
D K Kakru
Department of Clinical Microbiology, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir - 190 011
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 17643019 
One hundred and twenty methicillin resistant Staphylococcus aureus (MRSA) strains were checked for minimum inhibitory concenteration (MIC) of vancomycin. The results showed that 98 strains (81.7 %) had MIC < 4µg/mL, 18 strains (15 %) had MIC 8 µg/mL, and 4 (03.3%) had MIC 16 µg/mL which being borderline between sensitive (< 4µg/mL) and resistant (>32µg/mL) values points towards possible emergence of low level vancomycin resistance in the organisms and may explain the reasons of delayed therapeutic success of vancomycin in S.aureus bacteraemia in some situations.
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