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Year : 1999  |  Volume : 17  |  Issue : 4  |  Page : 160-166

Changing face of nosocomial candidemia

Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012, India

Correspondence Address:
A Chakrabarti
Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012
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Source of Support: None, Conflict of Interest: None

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ABSTRACT: The number of nosocomial blood stream infections due to Candida species has increased dramatically over the last two decades though the overall picture in Indian hospitals is not clear, studies available from few institutions corroborates the same trend as the rest of the world. Since the introduction of fluconazole and intraconazole, many studies have documented an increase in prevalence of non-albicans Candida infections particularly with the agents that are less susceptible to triazoles. However, the issue of correlation between antifungal use and shift in the spectrum of fungal pathogens is still controversial. Possibly this is influenced by patient population, the various treatment regimens or other supportive measures employed at specific institutions. Many of the infections arise from endogenous sources. But increase in exogenous acquisition of newer agents or previously known agents from hands of health care workers, infusates and inanimate environment warrants a close surveillance and routine monitoring of this condition. Improved typing methods help to investigate the outbreaks and to understand the epidemiology of this disease. This would help us to plan the rational preventive measures.

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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04