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Year : 1999  |  Volume : 17  |  Issue : 4  |  Page : 160-165

Detection of extended spectrum BETA-LACTAMASE produces among surgical wound infections and burns patients in JIPER


Department of Microbiology, Jawaharlal Institute of Post-graduate Medical Education and Research, Pondicherry 605 006, India

Correspondence Address:
AN Ananthakrishnan
Department of Microbiology, Jawaharlal Institute of Post-graduate Medical Education and Research, Pondicherry 605 006
India
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Source of Support: None, Conflict of Interest: None


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ABSTRACT: A total of 100 consecutive patients admitted to the surgical wards with would infections (pre- and post-operative) and burns between May-June 1999 were studied. A total of 156 isolates were obtained from these patients. Of these, 32 organisms (20.5 percent of the total isolates) were found to be Extended spectrum beta-lactamase (ESBL) producers; the commonest were Escherichia coli (18 isolates) and Klebsiella pneumoniae (7 isolates). Among the different clinical samples, ESBL producers were found most commonly in cases of diabetic fasciitis (27 percent of isolates), and postoperative would infections (22.4 percent of isolates). Nineteen percent, 9.38 percent and 28.13 percent of the ESBL strains were found to be susceptible to gentamicin, ciprofloxacin and chloramphenicol respectively. Fifty three percent of the ESBL strains showed intermediate or sensitive zones to cefotaxime by the disk-diffusion method.






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