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Year : 1999  |  Volume : 17  |  Issue : 2  |  Page : 74-77

Correlation of morphotyping and extra cellular proteinase production as virulence markers in candida albicans


Department of clinical Microbiology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, J & K 190 011

Correspondence Address:
DK Kakru
Department of clinical Microbiology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, J & K 190 011

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Source of Support: None, Conflict of Interest: None


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ABSTRACT: Characterization of 45 strains of Candida albicans from symptomatic and asymptomatic individuals by morphotyping and proteinase production was done to establish a correlation between disease producing capability of a strain of C. albicans and its physiological properties. Of the 45 strains tested isolated from skin had the lowest proteinase activity while the strains isolated from blood had the highest proteinase activity and the strains isolated from oral cavity and genito-urinary tract had intermediate proteinase activity. Morphotype pattern of the four groups of strains showed a correlation with proteinase production, morphotypically virulent strains had higher extracellular proteinase production capacity.






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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04