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Year : 1998  |  Volume : 16  |  Issue : 2  |  Page : 72-74

Susceptibility of yeasts to pseudomonas aeruginosa


Sir Hurkisondas Nurrotamadas Medical Research Society, Raja Ram Mohan Roy Road, Mumbai 400 004

Correspondence Address:
RB Pal
Sir Hurkisondas Nurrotamadas Medical Research Society, Raja Ram Mohan Roy Road, Mumbai 400 004

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ABSTRACT: Pseudomonas spp produce a variety of metabolites, of which some exhibit antimicrobial activity. Of these antimicrobial substances, pyrrolnitrin has been known to possess antifungal activity. The present study was undertaken to determine the susceptibility pattern of different yeast species to Pseudomonas aeruginosa strains. Initially a panel of seven yeast strains was used to determine the antifungal activity of twenty three aeruginocin typed strains of P.aeruginosa. The different yeast species varied in their susceptibilities to the Pseudomonas strains. Maximum susceptibility was exhibited by Candida glabrata and Cryptococcus neoformans, which were suppressed by all the aeruginocin types tested. Some of the common aeruginocin types were then randomly selected and further tested with different isolates of the common yeasts species. The results confirmed the susceptibilities of C. glabrata and C. neoformans to the Pseudomonas strains. It was also observed that a greater percentage of C. tropicalis strains were resistant to the different aeruginocin types of Pseudomonas. As per our knowledge this is the first study of this kind. This simple method of testing may be effectively evolved into a typing system for yeast isolates.






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