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| Year : 1995 | Volume
: 13
| Issue : 3 | Page : 125-129 |
Occurrence of campylobacter jejuni/coli in cases of paediatric diarrhoea and guillain barre syndrome.
H Hariharan, C Kumaran, J Shanmugam, K Naseema, MD Nair, K Radhakrishnan, K Sabarinathan
Department of Microbiology and Neurology Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum 695 011
Correspondence Address:
H Hariharan
Department of Microbiology and Neurology Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum 695 011
 Source of Support: None, Conflict of Interest: None  | Check |
ABSTRACT: One hundred cases of paediatric diarrhoea, and 8 cases of Guillain Barre Syndrome (GBS) from Kerala, were studied for the occurrence of Campylobacter jejuni, C. coli and C.lari by bacteriological cultures of faecal specimens. Thirteen percent of faecal swabs from children with diarrhoea were positive for campylobacters. Nine of 11 isolates identified to species level were C.jejuni, and the remaining were C.coli. Of eight GBS cases studied, 3(37.5 percent) were positive for C.jejuni/coli. All the 3 patients showed high titres of antibodies against a standard strain of C.jejuni, in a microplate agglutination test Antimicrobial drug susceptibility tests by disk diffusion assay on isolates from paediatric diarrhoea cases revealed strains resistant to ampicillin, erythromycin, gentamicin and/or tobramycin. All three isolates from the GBS cases showed multiple drug resistance: two isolates against drugs including ampicillin and erythromycin, and the third one against nalidixic acid and norfloxacin.
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