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Year : 1995  |  Volume : 13  |  Issue : 2  |  Page : 86-89

Serum Complement (C3) levels during acute malarial infections and in the post treatment period

Department of Microbiology, J.N. Medical College. Aligarh Muslim University, Aligarh (UP)

Correspondence Address:
ME Siddique
Department of Microbiology, J.N. Medical College. Aligarh Muslim University, Aligarh (UP)

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Source of Support: None, Conflict of Interest: None

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ABSTRACT: The role of complement with special reference to malaria is not well documented. A total of 80 diagnosed patients, suffering from malaria were included in the study. Their serum C3 component of complement was estimated by single radial immuno-diffusion. The level showed a marked fall during the course of acute malaria infection among children and adults. (p0.01). The serum C3 level was found within normal level with reference to control on 10th, 20th and 30th days post-infection. The C3 level was markedly lower in children as compared to adults (p0.05). P. falciparum produced greater reductions in C3 levels than P. vivax, irrespective of age. Further considerable reduction in C3 levels was noted in children who developed acute cerebral malaria infected with P. falciparum.

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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

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