Indian Journal of Medical Microbiology IAMM  | About us |  Subscription |  e-Alerts  | Feedback |  Login   
  Print this page Email this page   Small font sizeDefault font sizeIncrease font size
 Home | Ahead of Print | Current Issue | Archives | Search | Instructions  
Users Online: 1840 Official Publication of Indian Association of Medical Microbiologists 
 ~   Next article
 ~   Previous article
 ~   Table of Contents

 ~   Similar in PUBMED
 ~  Search Pubmed for
 ~  Search in Google Scholar for
 ~   Citation Manager
 ~   Access Statistics
 ~   Reader Comments
 ~   Email Alert *
 ~   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded55    
    Comments [Add]    

Recommend this journal


Year : 1993  |  Volume : 11  |  Issue : 3  |  Page : 164-169

HLA B27 - Risk Factor In Families Of Ankylosing Spondylitis In South India.

Correspondence Address:
A. N Chandrasekaran

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

The association between Class I HLA antigens and Ankylosing spondylitias (A.S) among 42 first degree relatives of 20 AS probands and 40 unrelated A.S patients of South India was studied in Government General Hospital, Madras. 50 healthy persons served as controls. HLA B 27 and CW2 were not found in healthy controls whereas 85% of unrelated AS Patients and 92.3% of affected relatives of A.S probands were positive for B27. CW2 was present in 57.5% and 30.7% among unrelated patients and affected relatives respectively. Significant positive association (p<0.001) was observed with B27. CW6 was negatively associated with the disease. (P<0.1) No specific HLA marker could be identified among B27 negative A.S Patients. The incidence of A.S was more (34.2%) among B27 positive probands than among those of B27 negative probands (14.3%).


Print this article     Email this article

2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04