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Year : 1992  |  Volume : 10  |  Issue : 2  |  Page : 85-90

Transfer Of Infectious Drug Resistance - An In Vivo Study

Correspondence Address:
Mamatha Shetty

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Source of Support: None, Conflict of Interest: None

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In the present study, the in vivo transfer of drug resistance from resistant donor Escherichia coil strains to E, coli K12 and Salmonella typhimurium recipients in the gut of suckling rat is being reported. The frequency of transfer from E. coli to S. typhimurium 209 was found to be greater in comparison to recipient E. coli K12. Among the animal models used, transferable drug resistance took place at a higher rate in the suckling rat when compared to other animals like adult rabbit, suckling rabbit, adult mice etc. Single drug transfer was found to occur more often (20%) compared to double drug transfer in S. typhimurium (4.4%). The overall incidence of antibiotic resistance transfer by E. coli donors to both recipients was fairly high.


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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04