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Year : 1991  |  Volume : 9  |  Issue : 4  |  Page : 230-233

Effect Of Montoux Status On Serum Antitubercular Antibody Levels By ELISA

Correspondence Address:
Baldev Raj

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Source of Support: None, Conflict of Interest: None

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In this study 25 healthy Montoux negative persons (Group I), 25 healthy Montoux positive person who had received BCG vaccination in the past (Group II), 25 healthy Montoux positive persons who had not received BCG vaccination (Group III) and 25 persons suffering from active pulmonary tuberculosis (Group IV) were studied for IgG (gamma chain specific) reaction to antigen PPD- 298 by ELISA technique to see the effect of Montoux status of the individual on antibody titre. The mean antibody titre in Group III was more as compared to the Groups I and II, but on statistical analysis, the difference was not found to be significant. However, whereas, only one patient from Group I (Montoux negative) had antibody titre more than the cut off value, (absorbance A490 0.08 indicating a particular antibody titre) as many as 7 montoux positive patients (from Group II and III) had antibody titre more than the cut off point.

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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04