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Year : 1991  |  Volume : 9  |  Issue : 1  |  Page : 34-39

Candidal Gut Colonisation And Human ABO Blood Groups : A preliminary Report

Correspondence Address:
S Singh

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Blood groups of 90 patients, 45 with peptic ulcers, 25 with non ulcer dyspepsia and 20 with other non G.T. Diseases, were compared for their relative susceptibility to duodenal colonization by yeasts mainly of genus Candida. There was a significant difference in yeast isolation among patient of different blood group, A significantly fewer patients of blood group A had infection and colonization of yeasts than predicated, and there was an increased number of patients, in non-A blood groups, especially group O, colonized by various yeasts. The commonest yeast isolated was Candida albicans from all blood group patients. Candida krusei was found to colonies only blood group AB patients. No yeast other than C. albicans and C. tropicalis was isolated from blood group A patients. Our results, thus, suggest than an individual’s blood group substance may be a significant factor in the host response to fungal infections by virtue of their cross reactivity with surface antigens on these fungal cells.

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