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Year : 1991  |  Volume : 9  |  Issue : 1  |  Page : 13-15

Single Radial Haemolysis Test In Detection Of Rubella Antibody

Correspondence Address:
S. K Kher

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Source of Support: None, Conflict of Interest: None

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Two hundred and fifty eight sera of healthy adult blood donors, pregnant women and children in various age groups were tested for rubella antibody to determine their immune status using single radial haemolysis (SRH) test haemagglutination inhibition (HAI) test and enzyme linked immunosorbent assay (ELISA) test. The seroconversion was seen right from 0-5 years age group in which positivity of 22.73% was observed. The positivity increased with higher age groups and in the child bearing age group it reached 85%. All the sera tested positive by SRH test gave positive result by HAI and ELISA test also. However, the SRH and HAI test could not detect three and two immune sera respectively, out of 193 sera detected immune by ELISA test. SRH test was found to be efficient in detection of immune status to rubella. It was simple, economical and suitable for field application.

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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04