A Comparative Study of ELISA And Latex Agglutination Tests In Detecting HB sAg In Patients Of Viral Bepatitis, Voluntary Blood Donors And Healthy Pregnant Women.

N Jindal; A Aggarwal; H Prabhakar; S Arora

Indian Journal of Medical Microbiology

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Year : 1989 | Volume : 7 | Issue : 4 | Page : 160-163

A Comparative Study of ELISA And Latex Agglutination Tests In Detecting HB sAg In Patients Of Viral Bepatitis, Voluntary Blood Donors And Healthy Pregnant Women.

N Jindal, A Aggarwal, H Prabhakar, S Arora

Correspondence Address:
N Jindal

Source of Support: None, Conflict of Interest: None

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Two hundred and seventy serum samples from patients of acute viral hepatitis (78), voluntary blood donors (132) and healthy pregnant women (60) were investigated for the presence of HbsAg and Latex agglutination tests. The prevalence of HbsAG with ELISA test was 16.6%, 3.8% and by Latex agglutination test 15.4%, 3% and 3.3% in the three respective groups. Compared with ELISA, Latex agglutination lest showed a sensitivity of 90% and specificity of 99.2%. The present study confirmed the higher sensitivity of ELISA test over latex agglutination test in detecting HB sAg in human serum.

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