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| Year : 1988 | Volume
: 6
| Issue : 4 | Page : 275-282 |
Comparative Evaluation Of SAFA, PHA and SPRIA In Serodiagnosis Of Pulmonary Tuberculosis Using H37RV Sonicated Antigen
P. K Aggarwal, B. M Agarwal, V. L Lahiri, O. P Bansal, D. K Hazra, Y. C Sharma, R. K Chandoke, P. K Bhattacharjee
Correspondence Address:
P. K Aggarwal
 Source of Support: None, Conflict of Interest: None  | Check |
10 cases of typical mycobacteriosis, 12 cases of atypical mycobacteriosis and 10 healthy control subjects were studied for the presence of antibodies against soni-cate antigen of M. Tuberculosis H37Rv, using soluble antigen fluorescent antibody technique (SAFA), Passive haemagglutination test (PHA) and Solid phase radio-immunoassay technique (SPRIA). The positive reaction with these tests were 80%, 60% and 70% respectively in typical mycobacterial group, while it had been reduced to 41.6%, 8.3% and 8.3% respectively in atypical group. In contrast to this, normal healthy group had 30%, 10% and 20% positive reaction. The sensitivity and specificity of these tests were discussed.
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