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| Year : 1988 | Volume
: 6
| Issue : 4 | Page : 269-273 |
Susceptibility Of Coliforms To Augmentin
D Raghunath, V. C Ohri
Correspondence Address:
D Raghunath
 Source of Support: None, Conflict of Interest: None  | Check |
Susceptibility of 111 clinical isolates of coliforms was studied against Augmentin a formulation of amoxycillin and beta lactamase inhibitor clavulanic acid. These coliforms included Escherichia coli (74), Klebsiella spp (28) and Proteus spp (9). Minimum inhibitory concentrations of amoxycillin and Augmentin were determined against these coliforms by agar dilution technique. All the E. coli and Proteus spp were resistant to 16 mg/1 of amoxycillin whereas all Klebsiella spp were resistant to 32 mg/1. MIC of > 256 mg/1 of amoxycillin was seen in 93.2% of E. coli, 75% of Klebsiella spp and 89% of Proteus spp. MIC values against Augmentin were encouraging. 97.3% of E. coli, 96.4% of Klebsiella spp and 88.9% of Proteus spp were susceptible to 16 mg/1 of Augmentin. The value of Augmentin in treating ampicillin resistant organisms is highlighted.
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