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Year : 1987  |  Volume : 5  |  Issue : 2  |  Page : 101-106

Immunoglobulins And Complement (C3) Levels In Cerebrospinal Fluid In Cases Of Meningococcal Meningitis

Correspondence Address:
K Prakash

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Cerebrospinal fluid (CSF) samples collected from 50 clinically diagnosed cases of meningococcal meningitis and 20 age and sex matched controls were studied for the Immunoglobulins-IgG, IgA and IgM and complement (C3) levels. All the samples showed significant rise of IgG, IgA, and IgM and C3. However the levels were more marked as compared to controls in causes where Neisseria meningitidis could be demonstrated either by smear, Latex agglutination test (LAT) or culture. It was concluded that the high levels of immunoglobulins especially IgM which is normally absent in CSF along with the presence of C3 is diagnostic of pyogenic meningitis but does not indicate the causative organism.

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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

Online since April 2001, new site since 1st August '04