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| Year : 1984 | Volume
: 2
| Issue : 1 | Page : 25-31 |
Lymphocyte Subpopulations And Their Functions In Quinine Administered Rhesus Monkeys
R. N Prasad, R. C Mahajan, N. K Ganguly, S. K Garg
Correspondence Address:
R. N Prasad
 Source of Support: None, Conflict of Interest: None  | Check |
The effect of quinine on lymphocyte subpopulations and their blastogenic responses have been studied in normal Rhesus monkeys. A decrease in percentage of lymphocyte sub-population and its functions was observed from the 3rd day following drug administration. Maximum decline was observed on 6th day when the concentration of quinine in plasma was 6.75+0.54 mg/litre, However, the effect of drug was undetectable by the 14th day when the level of drug was zero. Effect of quinine on lymphocytes and their functions seems to be dependent on time of exposure and concentration of drug.
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