Indian J Med Microbiol Close
 

Figure 4: Short interference RNAs inhibitory effects against viral replication in serum-inoculated human hepatoma-7 cells. (a) Quantitative real-time polymerase chain reaction analysis of the viral load using 5' untranslated region-specific primers. (b and c) The inhibitory effects of short interference RNA mixtures on viral load containing different short interference RNAs targeting multiple regions of hepatitis C virus genome. Each experiment was performed in triplicate, and the data were collected as the mean of relative percentage decrease in viral load in short interference RNA-treated cells versus positive control (i.e., S 1a). The error bars indicate mean (n = 3) ± standard deviation with a value of P < 0.05 being statistically significant

Figure 4: Short interference RNAs inhibitory effects against viral replication in serum-inoculated human hepatoma-7 cells. (a) Quantitative real-time polymerase chain reaction analysis of the viral load using 5' untranslated region-specific primers. (b and c) The inhibitory effects of short interference RNA mixtures on viral load containing different short interference RNAs targeting multiple regions of hepatitis C virus genome. Each experiment was performed in triplicate, and the data were collected as the mean of relative percentage decrease in viral load in short interference RNA-treated cells versus positive control (i.e., S 1a). The error bars indicate mean (<i>n</i> = 3) ± standard deviation with a value of <i>P</i> < 0.05 being statistically significant