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Figure 3: Morphological changes of autophagy in infected-cells visualized with TEM. The structure of uninfected cells showed intact plasma and nuclear membranes (a). Double-or multilayer-membrane of autophagic vacuole (AV) was observed in WT-MEFs infected by ST10 and ST8 (b, c). RAPA-treated WT-MEFs infected by ST8, ST10 and SR-11 at the early time points of infection (d, e and f). Black arrows show AV

Figure 3: Morphological changes of autophagy in infected-cells visualized with TEM. The structure of uninfected cells showed intact plasma and nuclear membranes (a). Double-or multilayer-membrane of autophagic vacuole (AV) was observed in WT-MEFs infected by ST<sub>10</sub> and ST<sub>8</sub> (b, c). RAPA-treated WT-MEFs infected by ST<sub>8</sub>, ST<sub>10</sub> and SR-11 at the early time points of infection (d, e and f). Black arrows show AV