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Year : 2019  |  Volume : 37  |  Issue : 3  |  Page : 351--357

Seroprevalence of Toxoplasmosis at a Tertiary Care Centre in North India from 2004 to 2014

Abhishek Mewara, Shreya Singh, Sumeeta Khurana, Parakriti Gupta, Rakesh Sehgal 
 Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Dr. Sumeeta Khurana
Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012
India

Purpose: This study was carried out to determine the seroprevalence of anti-Toxoplasma gondii antibodies in different groups of patients at a tertiary care hospital in North India. Materials and Methods: Clinical and demographic data such as age and gender of patients who had undergone testing for the presence of anti-T. gondii IgG and IgM antibodies between January 2004 and October 2014 were retrospectively analysed. Results: Amongst the 8397 serum samples, an overall seropositivity of 21% (n = 1763) and IgG and IgM seropositivity of 5.7% (n = 481) and 15.3% (n = 1282) were respectively observed. Compared to the period of 2004–2012 (median seroprevalence: 23.6%), a decline in seropositivity to 9.7% in 2013 and 8.1% in 2014 was noted. A rising seroprevalence with age and a higher seroprevalence in females versus males (29.5%, n = 1179 vs. 13.3%, n = 584) were recorded. The highest seroprevalence was observed in suspected ocular toxoplasmosis (47.2%, n = 47), followed by neurological (26.8%, n = 77), human immunodeficiency virus/acquired immunodeficiency syndrome (18.9%, n = 267), post-transplant (17.1%, n = 12) and congenital (7.2%, n = 144) toxoplasmosis. In patients screened for Toxoplasma exposure, the seropositivity was 47.8% (n = 11) in transplant screening and 44.9% (n = 781) in antenatal screening. Conclusion: Toxoplasma infection is highly prevalent in the population of North India across various clinical categories of patients. Future studies focusing on continuous monitoring of seroprevalence trends and elucidation of the risk factors associated with seropositivity in more defined groups of patients are needed.

How to cite this article:
Mewara A, Singh S, Khurana S, Gupta P, Sehgal R. Seroprevalence of Toxoplasmosis at a Tertiary Care Centre in North India from 2004 to 2014.Indian J Med Microbiol 2019;37:351-357

How to cite this URL:
Mewara A, Singh S, Khurana S, Gupta P, Sehgal R. Seroprevalence of Toxoplasmosis at a Tertiary Care Centre in North India from 2004 to 2014. Indian J Med Microbiol [serial online] 2019 [cited 2020 Aug 5 ];37:351-357
Available from: http://www.ijmm.org/article.asp?issn=0255-0857;year=2019;volume=37;issue=3;spage=351;epage=357;aulast=Mewara;type=0