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Year : 2018  |  Volume : 36  |  Issue : 4  |  Page : 587--589

Deciphering polymyxin B minimum inhibitory concentration from colistin minimum inhibitory concentration and vice versa: An analysis on 156 carbapenem-resistant Enterobacteriaceae isolates

Bijayini Behera, Jayanti Jena, Punyatoya Kar, Srujana Mohanty, Ashoka Mahapatra 
 Department of Microbiology, AIIMS, Bhubaneswar, Odisha, India

Correspondence Address:
Dr. Bijayini Behera
Associate Professor, Department of Microbiology, AIIMS, Bhubaneswar - 751 019, Odisha
India

The susceptibility determination to polymyxins (colistin and polymyxin B) remains a challenge for clinical microbiology laboratories. We evaluated the minimum inhibitory concentration (MIC) of both antimicrobials by the broth microdilution method in a selected subset of 156 carbapenem-resistant Enterobacteriaceae (CRE) isolates. Good concordance between polymyxin B and colistin MIC values was obtained, and there was 98% categorical agreement in CRE isolates. Future large-scale multicentre study is needed to draw conclusion if the MIC of colistin can be used to extrapolate the MIC of polymyxin B and vice versa.

How to cite this article:
Behera B, Jena J, Kar P, Mohanty S, Mahapatra A. Deciphering polymyxin B minimum inhibitory concentration from colistin minimum inhibitory concentration and vice versa: An analysis on 156 carbapenem-resistant Enterobacteriaceae isolates.Indian J Med Microbiol 2018;36:587-589

How to cite this URL:
Behera B, Jena J, Kar P, Mohanty S, Mahapatra A. Deciphering polymyxin B minimum inhibitory concentration from colistin minimum inhibitory concentration and vice versa: An analysis on 156 carbapenem-resistant Enterobacteriaceae isolates. Indian J Med Microbiol [serial online] 2018 [cited 2019 Dec 10 ];36:587-589
Available from: http://www.ijmm.org/article.asp?issn=0255-0857;year=2018;volume=36;issue=4;spage=587;epage=589;aulast=Behera;type=0