Indian Journal of Medical Microbiology Home 

ORIGINAL ARTICLE
[View FULLTEXT] [Download PDF]
Year : 2015  |  Volume : 33  |  Issue : 5  |  Page : 93--96

Susceptibility characterisation of Candida spp. to four essential oils

CC Rath, S Mohapatra 
 Post Graduate Department of Botany, North Orissa University, Baripada, Orissa, India

Correspondence Address:
C C Rath
Post Graduate Department of Botany, North Orissa University, Baripada, Orissa
India

In the present investigation, anti-Candida activity of four essential oils i.e. Black cumin (Nigella sativa), Curry leaf (Murraya koienigii), Ajwain (Trachiyspirum ammi), and Betel leaf (Piper betel) were screened against four human pathogenic species of Candida viz. Candida albicans, Candida tropicalis, Candida glabrata, and Candida parapsilosis. The minimum inhibitory concentration (MIC) values of the oils ranged between 15.62 and 250 μl/ml while studied through tube dilution method. The oils retained their anti-Candida activities even after heat treatment (at 45ΊC, 60ΊC, 100ΊC for 1 hour) and also on autoclaving. Both Ajwain and Black Cumin leaf oils showed better anti-Candida activity against Candida albicans, resulting in an irreversible damage to the cells. The anti-Candida activity of these essential oils could be attributable to the membrane inhibition mechanism. The activity of the oils is reported to be microbicidal (Candida-cidal).

How to cite this article:
Rath C C, Mohapatra S. Susceptibility characterisation of Candida spp. to four essential oils.Indian J Med Microbiol 2015;33:93-96

How to cite this URL:
Rath C C, Mohapatra S. Susceptibility characterisation of Candida spp. to four essential oils. Indian J Med Microbiol [serial online] 2015 [cited 2019 Oct 14 ];33:93-96
Available from: http://www.ijmm.org/article.asp?issn=0255-0857;year=2015;volume=33;issue=5;spage=93;epage=96;aulast=Rath;type=0