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Year : 2009  |  Volume : 27  |  Issue : 2  |  Page : 139--141

Seroprevalence of hepatitis E virus immunoglobulin G and M antibodies in adults: A hospital-based study

K Bashir1, N Hussain1, S Hasnain1, S Elahi2 
1 Department of Microbiology and Molecular Genetics, University of Punjab, Quaid-e-Azam Campus, Lahore-54 590, Pakistan
2 Centre for Nuclear Medicine, PO Box 53; Mayo Hospital, Lahore, Pakistan

Correspondence Address:
K Bashir
Department of Microbiology and Molecular Genetics, University of Punjab, Quaid-e-Azam Campus, Lahore-54 590
Pakistan

Sporadic cases of Hepatitis E virus (HEV) infection occur throughout the year in Pakistan. The aim of this study was to determine the prevalence of HEV immunoglobulin (Ig) G and IgM antibodies in 93 hepatitis B and C-negative patients as such patients are not routinely tested further despite having signs and symptoms of hepatitis. Anti-HEV IgG and IgM were detected by the enzyme-linked immunosorbant assay technique. Among them five patients (5.4%) were positive for HEV IgG and IgM, with an average age of 30.95 15.35 years. Hepatitis E infection was independent of the sex. Liver function tests of hepatitis E-positive IgG and IgM patients showed increased values of serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, alkaline phosphatase and bilirubin that indicate damaged hapatocytes and malfunctioning of the liver.

How to cite this article:
Bashir K, Hussain N, Hasnain S, Elahi S. Seroprevalence of hepatitis E virus immunoglobulin G and M antibodies in adults: A hospital-based study.Indian J Med Microbiol 2009;27:139-141

How to cite this URL:
Bashir K, Hussain N, Hasnain S, Elahi S. Seroprevalence of hepatitis E virus immunoglobulin G and M antibodies in adults: A hospital-based study. Indian J Med Microbiol [serial online] 2009 [cited 2020 Apr 8 ];27:139-141
Available from: http://www.ijmm.org/article.asp?issn=0255-0857;year=2009;volume=27;issue=2;spage=139;epage=141;aulast=Bashir;type=0