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Year : 2008  |  Volume : 26  |  Issue : 3  |  Page : 243--245

Metallo-β-lactamase-producing clinical isolates of Acinetobacter species and Pseudomonas aeruginosa from intensive care unit patients of a tertiary care hospital

S Irfan, A Zafar, D Guhar, T Ahsan, R Hasan 
 Clinical Laboratory, Department of Pathology and Microbiology, Aga Khan University and Hospital, Stadium Road, Karachi, Pakistan

Correspondence Address:
S Irfan
Clinical Laboratory, Department of Pathology and Microbiology, Aga Khan University and Hospital, Stadium Road, Karachi
Pakistan

Prompt detection of metallo-β-lactamase (MBL) producing isolates is necessary to prevent their dissemination. Frequency of MBLs producing strains among multidrug resistant (MDR) Acinetobacter species and Pseudomonas aeruginosa was evaluated in critical care patients using imipenem-EDTA disk method. One hundred MDR Acinetobacter spp. and 42 Pseudomonas aeruginosa were checked for MBL production, from January to June 2001. MBL was produced by 96.6 % of imipenem-resistant Acinetobacter isolates, whereas 100% imipenem-resistant Pseudomonas aeroginosa isolates were MBL producers. Carbapenem resistance in MDR Acinetobacter spp. and Pseudomonas aeruginosa isolates in this study was due to MBLs. This calls for strict infection control measures to prevent further dissemination.

How to cite this article:
Irfan S, Zafar A, Guhar D, Ahsan T, Hasan R. Metallo-β-lactamase-producing clinical isolates of Acinetobacter species and Pseudomonas aeruginosa from intensive care unit patients of a tertiary care hospital.Indian J Med Microbiol 2008;26:243-245

How to cite this URL:
Irfan S, Zafar A, Guhar D, Ahsan T, Hasan R. Metallo-β-lactamase-producing clinical isolates of Acinetobacter species and Pseudomonas aeruginosa from intensive care unit patients of a tertiary care hospital. Indian J Med Microbiol [serial online] 2008 [cited 2019 Jul 20 ];26:243-245
Available from: http://www.ijmm.org/article.asp?issn=0255-0857;year=2008;volume=26;issue=3;spage=243;epage=245;aulast=Irfan;type=0