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Year : 2008  |  Volume : 26  |  Issue : 2  |  Page : 187--189

Gastrointestinal histoplasmosis presenting as colonic pseudotumour

S Sehgal, R Chawla, PS Loomba, B Mishra 
 Department of Microbiology, GB Pant Hospital, New Delhi - 110 002, India

Correspondence Address:
R Chawla
Department of Microbiology, GB Pant Hospital, New Delhi - 110 002
India

We report a case of gastrointestinal histoplasmosis in a 45-year-old HIV positive man who was misdiagnosed as a case of colonic cancer. The patient presented with low-grade fever, pain in lower abdomen, anorexia and weight loss of six months duration. On examination a lump in the left iliac fossa was detected. Colonoscopy revealed stricture and ulcerated growth in the sigmoid colon. Radiological investigations suggested malignant/inflammatory mass in the sigmoid colon with luminal compromise. Patient was operated and ulcerated tissue was sent for histopathological examination, which revealed numerous intracellular, 2-4 μm, oval, narrow-based budding yeast cells suggestive of Histoplasma capsulatum . Subsequently, the patient developed fluffy opacities on X-ray chest. Examination of sputum revealed presence of acid-fast bacilli and yeast forms of H. capsulatum . Patient was started on amphotericin B but died on the seventeenth postoperative day. The diagnosis of histoplasmosis was made retrospectively. Atypical presentation and rarity of the disease led to this diagnostic pitfall. To the best of our knowledge this is the first report of gastrointestinal histoplasmosis presenting as colonic pseudotumour from India.

How to cite this article:
Sehgal S, Chawla R, Loomba P S, Mishra B. Gastrointestinal histoplasmosis presenting as colonic pseudotumour.Indian J Med Microbiol 2008;26:187-189

How to cite this URL:
Sehgal S, Chawla R, Loomba P S, Mishra B. Gastrointestinal histoplasmosis presenting as colonic pseudotumour. Indian J Med Microbiol [serial online] 2008 [cited 2019 Dec 12 ];26:187-189
Available from: http://www.ijmm.org/article.asp?issn=0255-0857;year=2008;volume=26;issue=2;spage=187;epage=189;aulast=Sehgal;type=0