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Year : 2008  |  Volume : 26  |  Issue : 1  |  Page : 65--67

Detection of extra-cellular enzymes of anaerobic gram-negative bacteria from clinically diseased and healthy sites

JM Nagmoti, CS Patil, MB Nagmoti, MB Mutnal 
 Department of Microbiology, Jawaharlal Nehru Medical College, Karnataka - 590 010, India

Correspondence Address:
J M Nagmoti
Department of Microbiology, Jawaharlal Nehru Medical College, Karnataka - 590 010
India

Anaerobic gram-negative bacteria (AGNB) produce enzymes that play a significant role in the development of disease. We tested 50 AGNB isolates, 25 each from clinically diseased and healthy human sites for in vitro production of caseinase, collagenase, etc. Majority of the isolates were Bacteroides fragilis and Porphyromonas gingivalis, which more commonly produced collagenase and haemolysin. Comparatively larger number of clinical AGNB produced collagenase (P = 0.004). No such difference was observed with other enzymes. Hence, collagenase is probably one of the key virulence markers of pathogenic AGNB, and the inhibitors targeting collagenases might help in the therapy of anaerobic infections.

How to cite this article:
Nagmoti J M, Patil C S, Nagmoti M B, Mutnal M B. Detection of extra-cellular enzymes of anaerobic gram-negative bacteria from clinically diseased and healthy sites.Indian J Med Microbiol 2008;26:65-67

How to cite this URL:
Nagmoti J M, Patil C S, Nagmoti M B, Mutnal M B. Detection of extra-cellular enzymes of anaerobic gram-negative bacteria from clinically diseased and healthy sites. Indian J Med Microbiol [serial online] 2008 [cited 2019 Nov 13 ];26:65-67
Available from: http://www.ijmm.org/article.asp?issn=0255-0857;year=2008;volume=26;issue=1;spage=65;epage=67;aulast=Nagmoti;type=0