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|Year : 2007 | Volume
| Issue : 2 | Page : 173--174
Non-typhoid Salmonellosis: Emerging infection in Pune?
V Shahane, V Muley, A Kagal, R Bharadwaj
Department of Microbiology, B. J. Medical College, Pune - 411 001, Maharashtra, India
Department of Microbiology, B. J. Medical College, Pune - 411 001, Maharashtra
|How to cite this article:|
Shahane V, Muley V, Kagal A, Bharadwaj R. Non-typhoid Salmonellosis: Emerging infection in Pune?.Indian J Med Microbiol 2007;25:173-174
|How to cite this URL:|
Shahane V, Muley V, Kagal A, Bharadwaj R. Non-typhoid Salmonellosis: Emerging infection in Pune?. Indian J Med Microbiol [serial online] 2007 [cited 2020 Jul 3 ];25:173-174
Available from: http://www.ijmm.org/text.asp?2007/25/2/173/32734
Salmonellosis is an important public health problem all over the world. It has been regarded as a worldwide problem in both man and animals.  In recent years, non-typhoid Salmonellae (NTS) are gaining eminence, but they are rarely reported in our country.
The present study was a retrospective study in and around Pune to assess the magnitude of non-typhoid Salmonella infections with the antibiotic susceptibility pattern of the organisms.
Over a five-year period (2000-2004), 85 isolates belonging to Salmonella spp. were isolated from clinical samples of patients of Sassoon General Hospital. They were further sent to the National Escherichia and Salmonella Center (NESC), Kasauli, for serotyping and confirmation. Antimicrobial susceptibility testing was done by Kirby Bauer disk diffusion method. 
Of the 85 salmonellae, 65.9% were Salmonella typhi , while 34.1% were non-typhoid salmonellae (NTS). The distribution of non-typhoid salmonellae is shown in the [table 1]. Majority of the NTS isolates were obtained from neonates (67.8%) and pediatric patients (14.2%). Blood samples yielded most of the NTS isolates, followed by stool samples and a single cerebrospinal fluid (CSF) sample. Human sources, as well as non-human sources like animals, birds, poultry, hospital wards, food supplies, milk, water and sewage, have been implicated in the spread of these NTS infections. 
Emergence of antimicrobial-resistant Salmonella strains is of great concern worldwide.
Antibiotics for the treatment of NTS infections are important in cases with bacteremia and focal lesions. However, they should be avoided in uncomplicated acute gastroenteritis as their unwarranted use can promote the emergence of drug-resistant strains.  Our study shows a high percentage of NTS isolates resistant to the commonly used drugs - i.e, 86% resistance was seen with ampicillin; and 72.4% resistance to cefotaxime, chloramphenicol and gentamicin was observed. No resistance was seen with amikacin and ciprofloxacin. Thus, our study highlights the fact that infections due to NTS seem to be an emerging problem in Pune and periodic accurate surveillance of NTS is necessary to portray the ongoing pattern of disease transmission, properties of various serotypes and their antibiotic sensitivity pattern. 
|1||Thong KL, Goh YL, Radu S, Noorzaleha S, Yasin R, Koh YT, et al . Genetic diversity of clinical and environmental strains of Salmonella enterica serotype weltervreden isolated in Malaysia. J Clin Microbiol 2002; 40 :2498-503.|
|2||Bauer AW, Kirby WM, Sherris JC, Jurek M. Antibiotic susceptibility testing by a standardized single method. Am J Clin pathol 1996; 45 :493-6.|
|3||Nath ML, Singh J, Bhandari SK. Salmonella pattern in India-II. Indian J Med Res 1970; 58 :1563-8.|
|4||Lee LA, Puhr ND, Maloney K, Bean NH, Tauxe RV. Increase in antimicrobial resistant Salmonella infections in the United States, 1989-1990. J Infect Dis 1994; 17: 128-33.|
|5||Chalker RB, Blaser MJ. A review of human salmonellosis: Magnitude of Salmonella infection in the United States. Rev Infect Dis 1988; 10 :111-21.|