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Year : 1992  |  Volume : 10  |  Issue : 2  |  Page : 126--132

Experimental Induction Of Cervical Carcinoma By Herpes Simplex Virus Type-2 In Rabbits : Gynaecological, Cytopathological And Immunological Evaluations.

M Elanchezhiyan1, K Udayasankar2, P Rajendran3, S Subramanian4, S.P Thyagarajan5 
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Correspondence Address:
M Elanchezhiyan


Evaluation of rabbits as experimental animal model for Herpes simplex virus type-2 (HSV-2) (HV-219 Strain) induced cervical carcinoma resulted in the development of a neoplastic condition in the form of leukoplakic patches only. On Papanicolaou’s staining, these areas revealed intra-nuclear vacuolization. The production of leukoplakic changes correlated with increase in the antibody level against HSV-2.

How to cite this article:
Elanchezhiyan M, Udayasankar K, Rajendran P, Subramanian S, Thyagarajan S. Experimental Induction Of Cervical Carcinoma By Herpes Simplex Virus Type-2 In Rabbits : Gynaecological, Cytopathological And Immunological Evaluations. Indian J Med Microbiol 1992;10:126-132

How to cite this URL:
Elanchezhiyan M, Udayasankar K, Rajendran P, Subramanian S, Thyagarajan S. Experimental Induction Of Cervical Carcinoma By Herpes Simplex Virus Type-2 In Rabbits : Gynaecological, Cytopathological And Immunological Evaluations. Indian J Med Microbiol [serial online] 1992 [cited 2020 Aug 10 ];10:126-132
Available from: http://www.ijmm.org/article.asp?issn=0255-0857;year=1992;volume=10;issue=2;spage=126;epage=132;aulast=Elanchezhiyan;type=0