Indian Journal of Medical Microbiology Home 

Year : 1984  |  Volume : 2  |  Issue : 1  |  Page : 49--55

Development Of Cell-Mediated Immunity In Guinea Pigs Immunized With Ribonucleic Acid Protein Fraction Of Entamoeba Histolytica

T Sundararaj1, A Sundararaj2, S Subramanian3 
1 
2 
3 

Correspondence Address:
T Sundararaj


The development of cell-mediated immunity at various time intervals was studied after immunization of guinea pigs with ribonucleic acid protein fraction (P-RNA) obtained from Enamoeba histolytica. The parameters for the study of cell-mediated immunity were delayed skin hypersensitivity (DH), macrophage migration (MMI) and macrophage aggregation (MA) elicited with P-RNA protein and lysate antigens from E. histolytica. Delayed hypersensitivity developed 14 days after immunization and persisted upto 60 days and in a few animals upto 90 days. Macrophage migration inhibition response with P-RNA antigen was more marked after 30 days of immunization. The response seen with other antigens were not much marked. Macrophage aggregation was prominent when elicited with P-RNA antigen and corresponded with MMI response.

How to cite this article:
Sundararaj T, Sundararaj A, Subramanian S. Development Of Cell-Mediated Immunity In Guinea Pigs Immunized With Ribonucleic Acid Protein Fraction Of Entamoeba Histolytica.Indian J Med Microbiol 1984;2:49-55

How to cite this URL:
Sundararaj T, Sundararaj A, Subramanian S. Development Of Cell-Mediated Immunity In Guinea Pigs Immunized With Ribonucleic Acid Protein Fraction Of Entamoeba Histolytica. Indian J Med Microbiol [serial online] 1984 [cited 2020 Jul 9 ];2:49-55
Available from: http://www.ijmm.org/article.asp?issn=0255-0857;year=1984;volume=2;issue=1;spage=49;epage=55;aulast=Sundararaj;type=0