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Year : 2018  |  Volume : 36  |  Issue : 1  |  Page : 119-120

In vitro analysis of the minimal inhibitory concentration values of different generations of anti-methicillin-resistant Staphylococcus aureus antibiotics


1 Department of Microbiology, Military Institute of Medicine, Warsaw, Poland
2 Department of Anaesthesiology and Intensive Therapy, Military Institute of Medicine, Warsaw, Poland

Correspondence Address:
Dr. Dariusz Tomaszewski
Department of Anaesthesiology and Intensive Therapy, Military Institute of Medicine, Szaserow 128 Street, 04-141 Warsaw
Poland
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmm.IJMM_17_136

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Methicillin-resistant Staphylococcus aureus (MRSA) resistance to antimicrobials may result in the increased risk of treatment failure. The objective of the study was to analyse in vitro MRSA susceptibility to vancomycin, linezolid, daptomycin, tigecycline, ceftaroline, dalbavancin, clindamycin, ciprofloxacin and trimethoprim/sulfamethoxazole. All MRSA strains isolated from hospitalised patients were analysed according to the current microbiological recommendations. Finally, a total of 124 MRSA strains were analysed; all were susceptible to tested antibiotics. Dalbavancin had the lowest minimum inhibitory concentration (MIC), and vancomycin the highest MIC value. There were 28/124 strains of MRSA susceptible for clindamycin, 36/124 for ciprofloxacin and 121/124 for trimethoprim/sulfamethoxazole. Dalbavancin was the most effective antimicrobial in our study.






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