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  Table of Contents  
CORRESPONDENCE
Year : 2015  |  Volume : 33  |  Issue : 5  |  Page : 163-164
 

Mucor -culture/molecular analysis necessary for identification


Department of Microbiology, Dr. Baba Saheb Ambedkar Hospital, Rohini, Delhi, India

Date of Submission27-May-2014
Date of Acceptance09-Oct-2014
Date of Web Publication6-Feb-2015

Correspondence Address:
S Duggal
Department of Microbiology, Dr. Baba Saheb Ambedkar Hospital, Rohini, Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0255-0857.150960

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How to cite this article:
Duggal S, Rongpharpi S R. Mucor -culture/molecular analysis necessary for identification. Indian J Med Microbiol 2015;33, Suppl S1:163-4

How to cite this URL:
Duggal S, Rongpharpi S R. Mucor -culture/molecular analysis necessary for identification. Indian J Med Microbiol [serial online] 2015 [cited 2019 Aug 20];33, Suppl S1:163-4. Available from: http://www.ijmm.org/text.asp?2015/33/5/163/150960


Dear Editor,

This is with reference to a case report by Angeline, et al., [1] 'Subcutaneous Mucor Zygomycosis with potential life threatening visceral complication', published in the Indian J Med Microbiol 2013;31 (2):182-4. We have some reservations regarding use of the word 'Mucor' in the title.

The authors have described a case of subcutaneous zygomycosis. Taxonomic organisation of zygomycetes has been described in a review by Ribes et al., [2] and in greater detail by Hoffman et al. [3] Mucor is one of the 57 genera of the order-Mucorales of the phylum Zygomycota. [3]

The findings in the case report included involvement of subcutaneous site and presence of eosinophilic granuloma that is Splendore Hoeppli phenomenon. These findings are commonly seen in infections due to Entomophthorales but rarely with Mucorales.[2] Response to fluconazole therapy has been described before for Entomophthorales[4] whereas resistance has been reported consistently against Mucorales.[5] Though the patient responded to fluconazole therapy and the authors have described it as an exception; in the absence of a culture report or molecular analysis, it may not be appropriate to label it as a case of 'Mucor' or 'Mucorales' as it may prompt the readers to use fluconazole for the treatment of other 'Mucor' infections.

 
 ~ References Top

1.
Angeline, Hanifah M, Balachandran G, Rajesh NG. Subcutaneous mucor zygomycosis with potential life-threatening visceral complication. Indian J Med Microbiol 2013;31:182-4.  Back to cited text no. 1
    
2.
Ribes JA, Vanover-Sams CL, Baker DJ. Zygomycetes in human disease. Clin Microbiol Rev 2000;13:236-301.  Back to cited text no. 2
    
3.
Hoffman K, Pawlowska J, Walther G, Wrzosek M, de Hoog GS, Benny GL, et al. The family structure of the Mucorales: A synoptic revision based on comprehensive multigene-genealogies. Persoonia 2013;30:57-76.  Back to cited text no. 3
    
4.
Gugnani HC, Ezeanolue BC, Khalil M, Amoah CD, Ajuiu EU, Oyewo EA. Fluconazole in the therapy of tropical deep mycoses. Mycoses 1995;38:485-8.  Back to cited text no. 4
    
5.
Kanafani ZA, Perfect JR. Antimicrobial resistance: Resistance to antifungal agents: Mechanisms and clinical impact. Clin Infect Dis 2008;46:120-8.  Back to cited text no. 5
    




 

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