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Year : 2013  |  Volume : 31  |  Issue : 2  |  Page : 177-179

Anti-ganglioside antibodies in patients with Guillain Barré syndrome and other neurological disorders


1 Department of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
C Vaishnavi
Department of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh
India
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Source of Support: ICMR, New Delhi, Conflict of Interest: None


DOI: 10.4103/0255-0857.115223

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A study was performed on 59 Guillain-Barré syndrome (GBS) cases, 58 neurological controls (NC) and 60 non-neurological controls (NNC) to investigate the association of anti-ganglioside antibodies in GBS and other neurological disorders. Campylobacter jejuni was isolated from 5.7% of GBS patients. Anti-ganglioside immunoglobulin G was present in 82% and immunoglobulin M in 46% in acute inflammatory demyelinating polyneuropathy patients, 70% and 44% respectively in acute motor axonal neuropathy subgroup and 38% each in acute motor sensory axonal neuropathy subgroup. Though high intensity of anti-gangliosides was present in the GBS patients, the NC patients also had adequate anti-gangliosides compared with the NNC group.






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2004 - Indian Journal of Medical Microbiology
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