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Year : 2013  |  Volume : 31  |  Issue : 1  |  Page : 60-63

Analysis of carbapenem-resistant Acinetobacter from a tertiary care setting in North India


Department of Microbiology, KG Medical University, Lucknow, Uttar Pradesh, India

Correspondence Address:
J Agarwal
Department of Microbiology, KG Medical University, Lucknow, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0255-0857.108724

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Multidrug-resistant (MDR) Acinetobacter baumannii is a worldwide concern as cause of serious nosocomial infections. We analysed 140 non-duplicate Acinetobacter sp. isolates from hospitalised patients in a tertiary care centre; 87% were MDR and 20% (28/140) meropenem resistant. Metallo-β-lactamase was produced by 16 of these, detected by ethylene-diamine-tetra-acetic acid disc synergy test. AmpC β-lactamase and efflux pump were present in 17 and 4 of the meropenem-resistant Acinetobacter, respectively. 9/16 MBL-positive isolates carried genes for carbapenem resistance as shown by polymerase chain reaction.






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