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 BRIEF COMMUNICATION
Year : 2010  |  Volume : 28  |  Issue : 2  |  Page : 162-163

Combined drug medium with isoniazid and rifampicin for identification of multi-drug resistant Mycobacterium tuberculosis


Department of Bacteriology, Tuberculosis Research Centre, (ICMR) Chennai - 600 031, India

Correspondence Address:
R Ramachandran
Department of Bacteriology, Tuberculosis Research Centre, (ICMR) Chennai - 600 031
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0255-0857.62497

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A low-cost method of detecting multi-drug resistant Mycobacterium tuberculosis (MDR-TB) with the possibility of quick adoption in a resource limited setting is urgently required. We conducted a study combining isoniazid and rifampicin in a single LJ medium, to detect MDR-TB strains. Combined and individual drug media showed 100% concordance for the detection of MDR-TB and susceptible strains by proportion method. Considering the results, combined isoniazid and rifampicin containing medium could be considered for use in settings where the sole detection of MDR-TB strains is justified.






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2004 - Indian Journal of Medical Microbiology
Published by Wolters Kluwer - Medknow

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