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 BRIEF COMMUNICATION
Year : 2010  |  Volume : 28  |  Issue : 2  |  Page : 155-157

Infection with hepatitis C virus genotype 3 - Experience of a tertiary health care centre in south India


1 Department of Clinical Virology, Christian Medical College, Vellore - 632 004, India
2 Centre for Infections, Health Protection Agency, London, United Kingdom
3 Department of Pathology, Christian Medical College, Vellore - 632 004, India
4 Department of Gastro Intestinal Sciences, Christian Medical College, Vellore - 632 004, India

Correspondence Address:
P Abraham
Department of Clinical Virology, Christian Medical College, Vellore - 632 004
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0255-0857.62495

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To analyse the response rate and the predictive values of virological, biochemical and histological factors on HCV antiviral therapy in HCV genotype 3 infected patients, we retrospectively studied 21 HCV genotype 3 infected patients, who underwent HCV antiviral therapy. Low (57%) sustained viral response (SVR) rate and significant association of SVR with normalization of alanine transaminase (ALT) levels were observed in our study. Absence of early viral response (EVR) showed high (80%) predictive value on SVR. Absence of EVR and normalisation of the ALT levels can predict the outcome of HCV antiviral therapy.






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2004 - Indian Journal of Medical Microbiology
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