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Year : 2009  |  Volume : 27  |  Issue : 1  |  Page : 51-54

SHV-28, an extended-spectrum β-lactamase produced by a clinical isolate of Klebsiella pneumoniae in south India


Department of Microbiology, International Centre for Cardio Thoracic and Vascular Diseases, A Unit of Frontier Lifeline, Chennai-600 101, Tamil Nadu, India

Correspondence Address:
S A Jemima
Department of Microbiology, International Centre for Cardio Thoracic and Vascular Diseases, A Unit of Frontier Lifeline, Chennai-600 101, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


PMID: 19172061

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SHV-28, an extended spectrum β-lactamase from a clinical isolate of Klebsiella pneumoniae , had an isoelectric point of 7.6 and a substrate profile showing preferential hydrolysis for cefotaxime over ceftazidime. It differed from SHV-1 by one amino acid substitution. The conserved S-T-F-K and K-T-G motifs were identified by SHV-28 protein sequencing.






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2004 - Indian Journal of Medical Microbiology
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