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Year : 2008  |  Volume : 26  |  Issue : 4  |  Page : 365-368

Molecular characterization of nosocomial CTX-M type β-lactamase producing Enterobacteriaceae from a tertiary care hospital in south India


Department of Microbiology, International Centre for Cardio Thoracic and Vascular Diseases, A Unit of Frontier Lifeline, R-30-C, Ambattur Industrial Estate Road, Mogappair, Chennai-600 101, Tamilnadu, India

Correspondence Address:
S A Jemima
Department of Microbiology, International Centre for Cardio Thoracic and Vascular Diseases, A Unit of Frontier Lifeline, R-30-C, Ambattur Industrial Estate Road, Mogappair, Chennai-600 101, Tamilnadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0255-0857.43581

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CTX-M group of extended spectrum β lactamases (ESBLs) represents a rapidly emerging problem in many countries. The prevalence of nosocomial bla CTX-M-1 producing Enterobacteriaceae strains has not been reported earlier in Indian hospitals. This study describes molecular subtyping of nosocomial bla CTX-M producing strains of Enterobacteriaceae . Polymerase chain reaction with primers specific for bla CTX-M-1 coding genes was used to identify 95 Enterobacteriaceae strains producing bla CTX-M positive isolates. Of the 95 bla CTX-M producing isolates, 45 strains were positive for bla CTX-M-1 . bla CTX-M-1 was found to be most prevalent in Klebsiella strains.






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2004 - Indian Journal of Medical Microbiology
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