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Year : 2008  |  Volume : 26  |  Issue : 3  |  Page : 256-258

Correlation between baseline CD4 + T-Lymphocyte count and plasma viral load in AIDS patients and their early clinical and immunological response to HAART: A preliminary study


1 Department of Microbiology, Maulana Azad Medical College, New Delhi - 110 002, India
2 Department of Medicine, Maulana Azad Medical College, New Delhi - 110 002, India

Correspondence Address:
H Gautam
Department of Microbiology, Maulana Azad Medical College, New Delhi - 110 002
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0255-0857.42039

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The aim of this study was to determine the clinical, immunological and virological status of newly diagnosed AIDS cases and to monitor their clinical and immunological response to HAART after a minimum period of three months. Forty three drug naive AIDS patients were enrolled. The most common presenting complaints were weight loss (74.4%), cough (72.1%) and diarrhoea (67.4%). Mean baseline CD4 cell count was 112 60 cells/μL and mean baseline plasma viral load of 31 patients studied was 192,686 copies/mL. Baseline plasma viral load was higher among patients with lower baseline CD4 cell count. During follow-up, 80.8% patients showed clinical improvement, while a CD4 cell count increased by ≥50 cells/μL in 84.6% cases. Mean CD4 cell count increased from 126 16.6 cells/μL at baseline to 278 196.7 cells/μL.






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2004 - Indian Journal of Medical Microbiology
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